New research is focusing on the synergistic relationship between vitamin K2 and vitamin D3, for bone and cardiovascular health.1 A group of naturally occurring and structurally similar, fat-soluble vitamins, vitamin K is essential for the proper utilization of calcium. Through its activation of the protein osteocalcin, vitamin K helps to bind newly absorbed calcium to the mineral matrix in bone. In addition, vitamin K has been found to help maintain bone mineral density by decreasing the activity of osteoclasts, a cell that breaks down the bone matrix.2 Vitamin K also provides critical cardiovascular protection by helping to activate matrix Gla protein (MGP), an inhibitor of circulatory calcification.3,4 Thus, vitamin K and vitamin D not only share similar qualities, but they also act synergistically within the body.5 Vitamin K2 with D3 includes 45 mcg of MenaQ7® PRO, the most widely studied form of vitamin K2 as MK-7, and 5,000 IU of vitamin D3 per capsule for optimal absorption and use by the body.